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Medical EncyclopediaICD-10: D25 Medically Verified

Uterine Fibroids (Leiomyomas)

Medically reviewed by the SEDU Clinical Review Board. Detailed pathophysiology, symptoms, evidence-based care guidelines, and pelvic health recovery protocols.

Clinical Overview

Non-cancerous (benign) tumors of the uterine muscle wall that can range in size from tiny seedlings to bulky masses, causing heavy menstrual bleeding and pressure.

Evidence-Based GuidelineConsult a specialist
Uterine Fibroids (Leiomyomas)

Image for disease-uterine-fibroids

SEDU Wellness Library

Associated Symptoms

  • Menorrhagia (Heavy Menstrual Bleeding)
  • Pelvic Heaviness & Fullness
  • Chronic Pelvic Pain
  • Urinary Urgency & Frequency

Treatment Pathways

  • Myomectomy (Fibroid Removal Surgery)
  • Combined Oral Contraceptive Pill
  • Lifestyle & Anti-Inflammatory Diet

Causes & Mechanisms

Monoclonal proliferation of smooth muscle cells, heavily influenced by estrogen and progesterone receptor sensitivity and extracellular matrix deposition.

Clinical Risk Factors

African ancestryFamily history of fibroidsObesityEarly onset of puberty

Related Conditions in Encyclopedia

Erectile Dysfunction (ED)

Polycystic Ovary Syndrome (PCOS)

Vaginismus

Clinical References & Journal Citations

  • 1NIH Fibroids Research Bulletin, 2022.
  • 2ACOG Practice Bulletin N.228 on Leiomyomas.

Medical Disclaimer

Educational and clinical guidance published in the SEDU Encyclopedia is compiled from peer-reviewed literature and reviewed by our clinical board for general health literacy. This material does not constitute personalized medical advice, formal diagnosis, or prescription. For acute pelvic pain, unusual bleeding, or persistent health concerns, consult a licensed healthcare provider promptly.